HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 5325505, compound → HCID 67640408, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 5325505 | HCID 5325505 | — |
| Reactant | Pravastatin Diol Lactone Di-(tert-butyldimethylsilyl) Ether | HCID 14600906 | — |
| Product | HCID 67640408 | HCID 67640408 | 16.2% |
Reaction Steps
A procedure similar to that described in Example 4, above, was followed, but using 1.0 g (1.8 mmol) of (4R,6R)-6-{2-[(1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-hexahydro-6-t-butyldimethylsilyloxy-8-hydroxy-2-methyl-1-naphthyl]ethyl}tetrahydro-4-t-butyldimethylsilyloxy-2H-pyran-2-one [prepared as described in Example B, above] and 888 mg (5.5 mmol) of 2-isopropyl-3-methylbutyryl chloride, to provide 198 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05827855 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-97553309f865412fa01b7cb9c86879ad |
| Source note | uspto-grants-1998_10 |