反应详情

Lindlar catalyst (250 mg) was prehydrogenated in hexane (40 ml) and pyridine (0.25 ml) for 30 min.; after addition of 1-Ethinyl-1-triethylsilanyloxy-cyclopentane (11.22 g; 50.0 mmole) dissolved in hexane (80 ml) hydrogenation was continued at ambient temperature and normal pressure until the uptake of hydrogen ceased; the catalyst was removed by filtration through a plug of neutral alumina (act. 3); after removal of the solvent under reduced pressure the crude product was purified by distillation. 1-Vinyl-1-triethylsilanyloxy-cyclopentane (B1) was obtained as a colourless oil; bp.: 100° C. (0.2 mbar), Kugelrohr.

1. customwas continued at ambient temperature
2. customthe catalyst was removed by filtration through a plug of neutral alumina (act. 3)
3. customafter removal of the solvent under reduced pressure the crude product
4. distillationwas purified by distillation