Sodium Hydroxide → HCID 44292535, compound

Participants

Reaction Steps

18.04 ml of 1N sodium hydroxide and 3.14 g of Ag2O were added to a solution of 380 mg of the product of Stage A in 8 ml of tetrahydrofuran and the mixture was stirred for 24 hours at ambient temperature. After adding 6N hydrochloric acid, extraction was carried out with ethyl acetate to obtain 380 mg of the expected product which is recrystallized from isopropanol to obtain a Rf=0.11 (ethyl acetate/cyclohexane 1/1).

Provenance & Evidence