HCID 22670002, compound → HCID 21841496, compound

HRID 400254Notes

Reaction equation

HRID 400254 reaction equation
[F:1][C:2]1[CH:7]=[C:6]([CH2:8][OH:9])[CH:5]=[C:4]([F:10])[C:3]=1[C:11]1[CH:16]=[CH:15][C:14]([O:17][CH2:18][C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)=[CH:13][CH:12]=1.CC(C)=[O:27].OS(O)(=O)=O.O=[Cr](=O)=O>C1CCCCC1.C(OCC)(=O)C>[F:1][C:2]1[CH:7]=[C:6]([C:8]([OH:27])=[O:9])[CH:5]=[C:4]([F:10])[C:3]=1[C:11]1[CH:12]=[CH:13][C:14]([O:17][CH2:18][C:19]2[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=2)=[CH:15][CH:16]=1

Participants

4

Reactant 2

HCID 22670002HCID 22670002, compoundHCID 131709961Jones' reagent

Product 1

HCID 21841496HCID 21841496, compound

Reagents, catalysts & solvents 1

HCID 21867204Cyclohexane ethylacetateSolvent

Procedure

An oxidation was carried out with 107 mg of the product of Stage B, with Jones' reagent under the conditions as described in Example 2, Stage C to obtain 86 mg of the expected product with a Rf=0.06 cyclohexane/ethyl acetate 7/3).

Sources & evidence

ORD record
ord-66afeda06304410499a1aaa9aedf5684
Source dataset
uspto-grants-1998_10
Patent number
US05827887

Reaction notes

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