HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → Benzeneacetyl chloride, 4-bromo-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | Benzeneacetic acid, 4-bromo- | HCID 74654 | — |
| Product | Benzeneacetyl chloride, 4-bromo- | HCID 181552 | 99% |
Reaction Steps
4-Bromophenylacetic acid (20 g, 0.093 mol) in thionyl chloride (29.46 mL, 0.4 mol) was heated under an argon atmosphere at 60° C. for 2 h. Removal of excess thionyl chloride in vacuo yielded a colourless oil (21.5 g), which was directly used in the next step as obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05827863 |
| Source dataset | uspto-grants-1998_10 |
| ORD ID | ord-cda79a0e6ec54b82862585162342a44c |
| Source note | uspto-grants-1998_10 |