反应详情

6.5 g benzyl 6-oxa-3-azabicyclo[3.1.0]hexane-3-carboxylate in 80 mL 33% aqueous ammonia solution was stirred 20 h in a closed vessel. The reaction was cooled and extracted with dichlormethane. The organic layer was washed with sodium chloride solution and evaporated to give 6.1 g of the desired product.

1. temperatureThe reaction was cooled
2. extractionextracted with dichlormethane
3. washThe organic layer was washed with sodium chloride solution
4. customevaporated