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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 400584Generated: October 25, 2026

6-Chloronicotinic acid → tert-Butyl (6-chloro-4-iodopyridin-3-yl)carbamate

https://huagongshe.com/reaction/400584

Reaction equation

Participants

RoleNameHCIDCharge
Reactant6-Chloronicotinic acidHCID 79222—
Reactant(4-Iodo-6-trifluoromethylpyridin-3-yl)carbamic acid tert-butyl esterHCID 60026433—
Producttert-Butyl (6-chloro-4-iodopyridin-3-yl)carbamateHCID 53415320—

Reaction Steps

The title product was prepared from 6-chloronicotinic acid in the same manner as in the preparation of (4-iodo-6-trifluoromethylpyridin-3-yl)carbamic acid tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08741897B2
Source datasetuspto-grants-2014_06
ORD IDord-b39dedeb26d24f1cb7ffce04479adf39
Source noteuspto-grants-2014_06