2-Fluoronicotinic acid → HCID 60026532, compound

HRID 400586Notes

Reaction equation

HRID 400586 reaction equation
[F:1]C1N=CC=CC=1C(O)=O.[C:11]([O:15][C:16](=[O:29])[NH:17][C:18]1[CH:19]=[N:20][C:21](C(F)(F)F)=[CH:22][C:23]=1[I:24])([CH3:14])([CH3:13])[CH3:12]>>[C:11]([O:15][C:16](=[O:29])[NH:17][C:18]1[C:19]([F:1])=[N:20][CH:21]=[CH:22][C:23]=1[I:24])([CH3:14])([CH3:13])[CH3:12]

Participants

3

Reactant 2

HCID 960892-Fluoronicotinic acidHCID 60026433(4-Iodo-6-trifluoromethylpyridin-3-yl)carbamic acid tert-butyl ester

Product 1

HCID 60026532HCID 60026532, compound

Procedure

The title product was prepared from 2-fluoronicotinic acid in the same manner as in the preparation of (4-iodo-6-trifluoromethylpyridin-3-yl)carbamic acid tert-butyl ester.

Sources & evidence

ORD record
ord-21b13158b2a3452ea96f72e87ab3c54c
Source dataset
uspto-grants-2014_06
Patent number
US08741897B2

Reaction notes

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