HuagongsheHuagongshe Chemistry Print Report · For research reference only
1H-Indazole-5-carbonitrile → N-hydroxy-1H-indazole-5-carboximidamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1H-Indazole-5-carbonitrile | HCID 11126384 | — |
| Reactant | N'-hydroxy-3H-benzimidazole-5-carboximidamide | HCID 178513241 | — |
| Product | N-hydroxy-1H-indazole-5-carboximidamide | HCID 72532767 | — |
Reaction Steps
The title compound was prepared following procedure described for Intermediate 1, step 2, but starting from 1H-indazole-5-carbonitrile (JW-Pharmalab, 0.50 g; 3.49 mmol) as a beige solid (560 mg, 91%). 1H NMR (DMSO-d6) δ 13.12 (s, 1H), 9.54 (s, 1H), 8.10 (s, 1H), 8.04 (s, 1H), 7.71 (d, J=8.7 Hz, 1H), 7.49 (d, J=8.7 Hz, 1H), 5.82 (bs, 2H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08741923B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-4e138912bab1469a89091263ce973bbe |
| Source note | uspto-grants-2014_06 |