HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 76787417, compound → tert-butyl 3-[7-{5-[4-(2-ethylpiperidin-1-yl)-3-(methoxymethyl)phenyl]-1,2,4-oxadiazol-3-yl}-3,4-dihydroisoquinolin-2(1H)-yl]propanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 76787417 | HCID 76787417 | — |
| Reactant | 4-(2-Ethylpiperidin-1-yl)-3-(methoxymethyl)benzoic acid hydrochloride | HCID 131731430 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | tert-butyl 3-[7-{5-[4-(2-ethylpiperidin-1-yl)-3-(methoxymethyl)phenyl]-1,2,4-oxadiazol-3-yl}-3,4-dihydroisoquinolin-2(1H)-yl]propanoate | HCID 67399684 | — |
Reaction Steps
Title compound was prepared following general procedure 2 starting from Intermediate 22 (188 mg; 0.6 mmol) and Intermediate 25 (182 mg; 0.6 mmol). The reaction mixture was diluted with EtOAc, washed with water and brine and evaporated under vacuum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08741923B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-5f28af8160164a93921b0165d9dfa8f3 |
| Source note | uspto-grants-2014_06 |