HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(Bromomethyl)-3-chloro-1,4-difluorobenzene → HCID 71558515, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(Bromomethyl)-3-chloro-1,4-difluorobenzene | HCID 2773549 | — |
| Reactant | 5-tert-Butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine | HCID 71558205 | — |
| Reactant | HCID 178441789 | HCID 178441789 | — |
| Product | HCID 71558515 | HCID 71558515 | — |
Reaction Steps
In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 61), the title compound was prepared from 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and 2-(bromomethyl)-3-chloro-1,4-difluorobenzene and isolated as white solid (8.0 mg, 44%). MS (m/e): 443.4 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08741906B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-8afe0370a2b1436a8056963a62ff74e8 |
| Source note | uspto-grants-2014_06 |