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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 400922Generated: November 1, 2026

HCID 59820596, compound → HCID 86683329, compound

https://huagongshe.com/reaction/400922

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59820596HCID 59820596—
Reactant5-tert-Butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 71558205—
ReactantHCID 178441789HCID 178441789—
ProductHCID 86683329HCID 86683329—

Reaction Steps

In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 61), the title compound was prepared from 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and 3-(iodomethyl)-4-methyl-5-(methylsulfonyl)-4H-1,2,4-triazole and isolated as white solid. MS (m/e): 456.3 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08741906B2
Source datasetuspto-grants-2014_06
ORD IDord-b88a3638758c4ea0b428c7bdbd6c67d4
Source noteuspto-grants-2014_06