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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 400924Generated: November 1, 2026

HCID 57941503, compound → HCID 86683333, compound

https://huagongshe.com/reaction/400924

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 57941503HCID 57941503—
Reactant5-tert-Butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 71558205—
ReactantHCID 178441789HCID 178441789—
ProductHCID 86683333HCID 86683333—

Reaction Steps

In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 61), the title compound was prepared from 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and 4-(bromomethyl)-3-(trifluoromethyl)-1-trityl-1H-pyrazole and used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08741906B2
Source datasetuspto-grants-2014_06
ORD IDord-cfffcafd9f2b4709badfd19ce502016f
Source noteuspto-grants-2014_06