HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Chloromethyl)-3-(trifluoromethyl)-1,2,4-oxadiazole → HCID 86683339, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Chloromethyl)-3-(trifluoromethyl)-1,2,4-oxadiazole | HCID 13563301 | — |
| Reactant | 5-tert-Butyl-7-(3,3-difluoro-pyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine | HCID 71558205 | — |
| Reactant | HCID 178441789 | HCID 178441789 | — |
| Product | HCID 86683339 | HCID 86683339 | — |
Reaction Steps
In analogy to the procedure described for the synthesis of 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3-ethyl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 61), the title compound was prepared from 5-tert-butyl-7-(3,3-difluoropyrrolidin-1-yl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and 5-(chloromethyl)-3-(trifluoromethyl)-1,2,4-oxadiazole and isolated as brown gum. MS (m/e): 433.3 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08741906B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-43ede8a7eabe4ba585b5e9404625ccc5 |
| Source note | uspto-grants-2014_06 |