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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 400968Generated: October 28, 2026

5-tert-Butyl-3-(2-chloro-benzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine → HCID 86683379, compound

https://huagongshe.com/reaction/400968

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-tert-Butyl-3-(2-chloro-benzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 1433953—
Reactant3-Methyl-5-(pyrrolidin-2-yl)-1,2-oxazoleHCID 15186065—
Reactant5-tert-butyl-7-chloro-3-(2-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 86683284—
ProductHCID 86683379HCID 86683379—

Reaction Steps

In analogy to the procedure described for the synthesis of 5-tert-butyl-3-(2-chlorobenzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 1, step c), the title compound was prepared from 5-tert-butyl-7-chloro-3-(2-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and 3-methyl-5-(pyrrolidin-2-yl)isoxazole. MS (m/e): 452.4

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08741906B2
Source datasetuspto-grants-2014_06
ORD IDord-445b60bfbebc41369434db09346f55c1
Source noteuspto-grants-2014_06