Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 400976Generated: October 29, 2026

4-Hydroxypyrrolidine → HCID 78111043, compound

https://huagongshe.com/reaction/400976

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-HydroxypyrrolidineHCID 98210—
Reactant5-tert-Butyl-3-(2-chloro-benzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 1433953—
Reactant5-tert-butyl-7-chloro-3-(2-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidineHCID 86683284—
ProductHCID 78111043HCID 78111043—

Reaction Steps

In analogy to the procedure described for the synthesis of 5-tert-butyl-3-(2-chlorobenzyl)-7-morpholin-4-yl-3H-[1,2,3]triazolo[4,5-d]pyrimidine (example 1, step c), the title compound was prepared from 5-tert-butyl-7-chloro-3-(2-chlorobenzyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine and pyrrolidin-3-ol and isolated as colorless foam. MS (m/e): 387.4 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08741906B2
Source datasetuspto-grants-2014_06
ORD IDord-38f5a300972f4c758c86043da2013144
Source noteuspto-grants-2014_06