Benzeneacetic acid, 4-bromo- → 2-(4-Bromophenyl)-1-phenylethan-1-one
Reaction equation
CO[C:3]1[CH:4]=[C:5]([CH2:11][C:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:13])[CH:6]=[CH:7][C:8]=1OC.[Br:20]C1C=CC(CC(O)=O)=CC=1>>[Br:20][C:8]1[CH:7]=[CH:6][C:5]([CH2:11][C:12]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)=[O:13])=[CH:4][CH:3]=1Participants
3
Procedure
Prepared by the same two step synthesis described in the synthesis of Intermediate 7, starting from 2-(4-bromophenyl)acetic acid.
Workup
- customPrepared by the same two step synthesis
Sources & evidence
- ORD record
- ord-b1060e48152b4990a85e721cb3986679
- Source dataset
- uspto-grants-2014_06
- Patent number
- US08741915B2
Reaction notes
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