化工社化工社 化学情報印刷レポート · 研究参考用
1-(3,5-Dichlorophenyl)-2-phenylethanone → 3'-Chloro-4'-fluoro-2-phenylacetophenone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 1-(3,5-Dichlorophenyl)-2-phenylethanone | HCID 2758146 | — |
| 反応物 | 4-Bromo-2-chloro-1-fluorobenzene | HCID 3543065 | — |
| 生成物 | 3'-Chloro-4'-fluoro-2-phenylacetophenone | HCID 2757565 | 20% |
反応手順
Prepared following the procedure described in Intermediate 13, starting from 4-bromo-2-chloro-1-fluorobenzene, where the crude product was purified by column chromatography (PE: EtOAc=100:1) to afford Intermediate 17 (110 mg, yield 20.0%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08741915B2 |
| 出典データセット | uspto-grants-2014_06 |
| ORD ID | ord-8c455b26ddc54e7e96a2ea6228ccf995 |
| 出典メモ | uspto-grants-2014_06 |