3-Fluoro-4-hydroxybenzaldehyde → HCID 18452164, compound
Reaction equation
Cl[C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH:5]=[O:6].[F:14]C1C=C(C=CC=1O)C=O>>[F:14][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH:5]=[O:6]Participants
3
Procedure
Followed procedure described for Intermediate 59, starting with 3-fluoro-4-hydroxybenzaldehyde. Desired product isolated in 53% yield.
Sources & evidence
- ORD record
- ord-3654779f7de549d9a04253839aa2b9fd
- Source dataset
- uspto-grants-2014_06
- Patent number
- US08741915B2
Reaction notes
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