HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 401275Generated: October 26, 2026
Dimethylformamide → [2-(5-Fluoro-2,4-dinitro-phenyl)-vinyl]-dimethyl-amine
https://huagongshe.com/reaction/401275
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Dimethylformamide dimethyl acetal | HCID 78373 | — |
| Reactant | 1-Fluoro-5-methyl-2,4-dinitrobenzene | HCID 520705 | — |
| Solvent | Water | HCID 962 | — |
| Product | [2-(5-Fluoro-2,4-dinitro-phenyl)-vinyl]-dimethyl-amine | HCID 57060726 | 63% |
Reaction Steps
A mixture of 1-fluoro-5-methyl-2,4-dinitro-benzene (10 g, 50 mmol), dimethoxymethyl-dimethylamine (11.9 g, 100 mmol) and DMF (50 mL) was heated at 100° C. for 4 h. The solution was cooled and poured into water. The red precipitate was collected via filtration, washed with water adequately and dried to give [2-(5-fluoro-2,4-dinitro-phenyl)-vinyl]-dimethyl-amine (8 g, 63%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08741925B2 |
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| Source dataset | uspto-grants-2014_06 |
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| ORD ID | ord-6f6e3b0b9c264bdc91c22d4cc7f9a5cb |
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| Source note | uspto-grants-2014_06 |
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