HRID40134

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID73784

Cyclopentane, iodo-

C5H9I

结构：CC(C)c1c(C(=O)NCc2ccc(C(F)(F)F)nc2)c2ccc(O)cc2n1Cc1ccccn1

HCID59762291

未命名化合物

2 次

PRODUCTS

生成物

结构：CC(C)c1c(C(=O)NCc2ccc(C(F)(F)F)nc2)c2ccc(OC3CCCC3)cc2n1Cc1ccccn1

HCID59762323

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 6-hydroxy-2-isopropyl-1-(pyridin-2-ylmethyl)-N-((6-(trifluoromethyl)pyridin-3-yl)methyl)-1H-indole-3-carboxamide (Compound 141) and cyclopentyl iodide by General Procedure N.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-3e1a967ccfb44c01b6c2f798819560ee
来源数据集: uspto-grants-2013_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08524917B2
来源说明: uspto-grants-2013_09

反应 SMILES

[OH:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:21]([NH:23][CH2:24][C:25]3[CH:26]=[N:27][C:28]([C:31]([F:34])([F:33])[F:32])=[CH:29][CH:30]=3)=[O:22])=[C:7]([CH:18]([CH3:20])[CH3:19])[N:8]2[CH2:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=2)=[CH:4][CH:3]=1.[CH:35]1(I)[CH2:39][CH2:38][CH2:37][CH2:36]1>>[CH:35]1([O:1][C:2]2[CH:10]=[C:9]3[C:5]([C:6]([C:21]([NH:23][CH2:24][C:25]4[CH:26]=[N:27][C:28]([C:31]([F:34])([F:33])[F:32])=[CH:29][CH:30]=4)=[O:22])=[C:7]([CH:18]([CH3:19])[CH3:20])[N:8]3[CH2:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][N:13]=3)=[CH:4][CH:3]=2)[CH2:39][CH2:38][CH2:37][CH2:36]1