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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 40137Generated: October 25, 2026

(5-Fluoropyridin-3-yl)methanamine → N-((5-Fluoropyridin-3-yl)methyl)-2-isopropyl-6-methoxy-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamide

https://huagongshe.com/reaction/40137

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(5-Fluoropyridin-3-yl)methanamineHCID 45116207—
Reactant2-isopropyl-6-methoxy-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxylic acidHCID 59762424—
ProductN-((5-Fluoropyridin-3-yl)methyl)-2-isopropyl-6-methoxy-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxamideHCID 59762442—

Reaction Steps

The title compound was prepared from 2-isopropyl-6-methoxy-1-(pyridin-2-ylmethyl)-1H-indole-3-carboxylic acid (Compound 139) and (5-fluoropyridin-3-yl)methanamine (Compound 145) by General Procedure C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524917B2
Source datasetuspto-grants-2013_09
ORD IDord-acb29aa9bd7c4bd68d5a4dca12ea6ad7
Source noteuspto-grants-2013_09