HuagongsheHuagongshe Chemistry Print Report · For research reference only
(6-Fluoro-5-methylpyridin-3-yl)boronic acid → 6-(6-Fluoro-5-methylpyridin-3-yl) imidazo[1,2-a]pyridine-3-carbaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (6-Fluoro-5-methylpyridin-3-yl)boronic acid | HCID 17750247 | — |
| Reactant | 6-Bromoimidazo[1,2-a]pyridine-3-carbaldehyde | HCID 21345676 | — |
| Product | 6-(6-Fluoro-5-methylpyridin-3-yl) imidazo[1,2-a]pyridine-3-carbaldehyde | HCID 86670605 | 44% |
Reaction Steps
The title compound was prepared by following the procedure as described for Intermediate 1 using 6-bromoimidazo[1,2-a]pyridine-3-carbaldehyde and 6-fluoro-5-methylpyridin-3-ylboronic acid. Yield: 44%; 1H NMR (DMSO-d6; 300 MHz): δ10.0 (s, 1H), 9.59 (s, 1H), 8.58-8.00 (m, 5H), 2.24 (s, 3H), MS: m/z 256(M+1)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08741932B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-a85e0c38be014b8b947e50ae0e69dff4 |
| Source note | uspto-grants-2014_06 |