HCID 57690820, compound → HCID 57690843, compound

Participants

Reaction Conditions

Reaction Steps

Manganese dioxide (5 g, 57.51 mmol) was added to a solution of (2-fluoropyridin-3-yl)(1-trityl-1H-imidazol-4-yl)methanol (1.3 g, 2.99 mmol) in dichloromethane (25 ml). The reaction mixture was heated to 75° C. and stirred for 18 hours. The crude mixture was cooled down to room temperature and filtered through a path of celite. The mother liquors were concentrated in vacuo to afford the title compound (1.1 g, 85% yield).

Provenance & Evidence