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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 401734Erstellt: 25. Oktober 2026

1-(4-Trifluoromethylphenyl)Ethylamine → 4-[(1,2,4-Thiadiazol-5-ylamino)sulfonyl]-N-[1-[4-(trifluoromethyl)phenyl]ethyl]benzamide

https://huagongshe.com/reaction/401734

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-(4-Trifluoromethylphenyl)EthylamineHCID 2782449—
Edukt4-[(1,2,4-Thiadiazol-5-ylamino)sulfonyl]benzoic acidHCID 57732214—
Produkt4-[(1,2,4-Thiadiazol-5-ylamino)sulfonyl]-N-[1-[4-(trifluoromethyl)phenyl]ethyl]benzamideHCID 57732003—

Reaktionsschritte

The title compound was prepared from 4-[(1,2,4-thiadiazol-5-ylamino)sulfonyl]benzoic acid (Preparation 29) and 1-[4-(trifluoromethyl)phenyl]ethanamine following the procedure described in Example 309. The reaction mixture was extracted from saturated sodium hydrogen carbonate into DCM and the crude product purified by preparative HPLC.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08741934B2
Quelldatensatzuspto-grants-2014_06
ORD IDord-4afe0ed5471e4f02bfc3311d06f68277
Quellennotizuspto-grants-2014_06