1,4-Dioxane hydrochloride → HCID 67374580, compound

HRID 402050Notes

Reaction equation

HRID 402050 reaction equation
[OH:1][CH:2]1[CH2:7][CH2:6][N:5]([CH2:8][CH2:9][NH:10][C:11]([C:13]2[N:14]=[N:15][C:16]([CH2:32][CH2:33][CH2:34][CH3:35])=[C:17]([C:19]3[CH:24]=[CH:23][C:22]([O:25][CH:26]4[CH2:31][CH2:30][CH2:29][CH2:28][CH2:27]4)=[CH:21][CH:20]=3)[CH:18]=2)=[O:12])[CH2:4][CH2:3]1.O1CCOCC1.[ClH:42]>>[ClH:42].[ClH:42].[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([CH2:8][CH2:9][NH:10][C:11]([C:13]2[N:14]=[N:15][C:16]([CH2:32][CH2:33][CH2:34][CH3:35])=[C:17]([C:19]3[CH:20]=[CH:21][C:22]([O:25][CH:26]4[CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]4)=[CH:23][CH:24]=3)[CH:18]=2)=[O:12])[CH2:6][CH2:7]1

Participants

3

Reactant 2

HCID 204431481,4-Dioxane hydrochlorideHCID 58438393HCID 58438393, compound

Product 1

HCID 67374580HCID 67374580, compound

Procedure

The title compound may be prepared by treatment of the amide with a HCl dioxane solution.

Sources & evidence

ORD record
ord-7e9ae1fdf6f143469d8449b6b70fc94e
Source dataset
uspto-grants-2014_06
Patent number
US08741900B2

Reaction notes

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