HuagongsheHuagongshe Chemistry Print Report · For research reference only
cis-4-Azidomethyl-1-tert-butoxycarbonyl-3-hydroxypiperidine → cis-4-Azidomethyl-piperidin-3-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | cis-4-Azidomethyl-1-tert-butoxycarbonyl-3-hydroxypiperidine | HCID 86657830 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | cis-4-Azidomethyl-piperidin-3-ol | HCID 86657829 | — |
Reaction Steps
A solution of cis-4-azidomethyl-3-hydroxy-piperidine-1-carboxylic acid tert-butyl ester (1.4 mmol, 360 mg) in dichloromethane (1 mL) and 4N HCl (2 mL) was stirred at room temperature for 2 h. Solvent was evaporated to give cis-4-azidomethyl-piperidin-3-ol and was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08741900B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-ede0607eba674992ab0d376d3c7ba52d |
| Source note | uspto-grants-2014_06 |