2-Fluoro-3-methoxybenzoic acid → HCID 178487694, compound

HRID 402158Notes

Reaction equation

HRID 402158 reaction equation
[F:1][C:2]1[C:10]([O:11][CH3:12])=[CH:9][CH:8]=[CH:7][C:3]=1C(O)=O.[OH:13][C:14]1C2C(=C(C)C(OC)=CC=2)[N:17]=[C:16]([C:27]2[S:28][CH:29]=[C:30]([CH:32]([CH3:34])[CH3:33])[N:31]=2)[CH:15]=1>>[F:1][C:2]1[C:10]([O:11][CH3:12])=[CH:9][CH:8]=[C:7]2[C:3]=1[N:17]=[C:16]([C:27]1[S:28][CH:29]=[C:30]([CH:32]([CH3:33])[CH3:34])[N:31]=1)[CH:15]=[C:14]2[OH:13]

Participants

3

Reactant 2

HCID 33906792-Fluoro-3-methoxybenzoic acidHCID 1784876922-(4-Isopropylthiazol-2-YL)-7-methoxy-8-methylquinolin-4-OL

Product 1

HCID 178487694HCID 178487694, compound

Procedure

The title compound was prepared from 2-fluoro-3-methoxybenzoic acid following the procedure (steps 1-5) reported for the preparation of 4-hydroxy-2-(4-isopropylthiazole-2-yl)-7-methoxy-8-methylquinoline (36): m/z=319 (M+H)+.

Sources & evidence

ORD record
ord-c05db9a28ce54a5fb6d338f88627ca8b
Source dataset
uspto-grants-2014_06
Patent number
US08741926B2

Reaction notes

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