Hydrazine → 3-Hydrazinyl-4-methyl-6-phenylpyridazine

HRID 40234Notes

Reaction equation

HRID 40234 reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)=[CH:6][C:7]=1[CH3:8].[NH2:15][NH2:16]>>[CH3:8][C:7]1[CH:6]=[C:5]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:4]=[N:3][C:2]=1[NH:15][NH2:16]

Participants

3

Reactant 2

HCID 9321HydrazineHCID 1199993-Chloro-4-methyl-6-phenylpyridazine

Product 1

HCID 30313733-Hydrazinyl-4-methyl-6-phenylpyridazine

Conditions

Temperature
100 °C

Procedure

3-Chloro-4-methyl-6-phenylpyridazine (0.510 g, 2.49 mmol) was dissolved in hydrazine (1.56 ml, 49.8 mmol) then the reaction mixture was heated at 100° C. for 1.5 hours. The precipitate that had formed in the mixture was collected and washed with iPrOH. The solid was dried under high vacuum to afford 1-(4-methyl-6-phenylpyridazin-3-yl)hydrazine as a pale yellow solid.

Workup

  1. customThe precipitate that had formed in the mixture
  2. customwas collected
  3. washwashed with iPrOH
  4. customThe solid was dried under high vacuum

Sources & evidence

ORD record
ord-0aaa04e4545440fbb21e6d7d09654bb4
Source dataset
uspto-grants-2013_09
Patent number
US08524900B2

Reaction notes

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