反应详情

As described for example 80c, 5-[3-(4-fluoro-phenyl)-5-methyl-3H-[1,2,3]triazol-4-ylmethoxy]-pyrazine-2-carboxylic acid (83 mg, 0.25 mmol), was converted, using isopropylamine instead of 4-aminotetrahydropyran, to the title compound (90 mg, 96%) which was obtained as an off white solid. MS: m/e=371.1 [M+H]+.