HCID 86655923, compound → HCID 71589531, compound

Participants

Reaction Steps

Compound 11a (0.024 g, 0.039 mmol, 1 eq) and 10% Pd/C catalyst (5 mg) were stirred in 4.0 mL of methanol overnight under an atmosphere of hydrogen. The catalyst was filtered and the reaction mixture was concentrated under vacuum yielding 0.011 g of 5-((benzo[d][1,3]-dioxol-5-ylmethylamino)methyl)-N,3-dihydroxy-4-(hydroxymethyl)picolinamide (69% yield) as a white solid; MS-ESI m/z 348 [MH]+.

Provenance & Evidence