HCID 44540473, compound → HCID 44541111, compound

Participants

Reaction Steps

Compound 12g (0.100 g, 0.184 mmol, 1 eq) and 10% Pd/C (5 mg) catalyst were stirred in methanol (4.0 mL) under a hydrogen atmosphere for 1 hour. The catalyst was filtered and the reaction mixture was concentrated under vacuum yielding 0.040 g of N5-(4-fluorobenzyl)-N2,3-dihydroxy-4-(methoxymethyl)-N5-methylpyridine-2,5-dicarboxamide (60% yield) as a white solid; MS-ESI m/z 364 [MH]+.

Provenance & Evidence