HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Chlorite → 8-(methoxycarbonyl)-2,2-dimethyl-4H-[1,3]dioxino[4,5-c]pyridine-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Chlorite | HCID 23668197 | — |
| Reactant | methyl 5-formyl-2,2-dimethyl-4H-[1,3]dioxino[4,5-c]pyridine-8-carboxylate | HCID 58360280 | — |
| Solvent | 2-Methylpropan-2-ol--water (1/1) | HCID 71401949 | — |
| Product | 8-(methoxycarbonyl)-2,2-dimethyl-4H-[1,3]dioxino[4,5-c]pyridine-5-carboxylic acid | HCID 58360283 | — |
Reaction Steps
8-(methoxycarbonyl)-2,2-dimethyl-4H-[1,3]dioxino[4,5-c]pyridine-5-carboxylic acid (23a) was synthesized from 5-Formyl-2,2-dimethyl-4H-[1,3]dioxino[4,5-c]pyridine-8-carboxylic acid methyl ester [J. Org. Chem. 1999, 64, 4537] 1 mmol and 1.5 mmol NaClO2 in t-butanol/water
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08742123B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-47522eaec8d649ff8621104d2ebea304 |
| Source note | uspto-grants-2014_06 |