HCID 58360291, compound → HCID 44540663, compound

HRID 402576Notes

Reaction equation

HRID 402576 reaction equation
[CH2:1]([O:8][CH2:9][CH2:10][N:11]([CH2:21][C:22]1[CH:27]=[N:26][C:25]([C:28]([O:30][CH3:31])=[O:29])=[C:24]2[O:32]C(C)(C)[O:34][CH2:35][C:23]=12)[CH2:12][CH2:13][C:14]1[CH:19]=[CH:18][C:17]([F:20])=[CH:16][CH:15]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)=O>[CH2:1]([O:8][CH2:9][CH2:10][N:11]([CH2:21][C:22]1[C:23]([CH2:35][OH:34])=[C:24]([OH:32])[C:25]([C:28]([O:30][CH3:31])=[O:29])=[N:26][CH:27]=1)[CH2:12][CH2:13][C:14]1[CH:15]=[CH:16][C:17]([F:20])=[CH:18][CH:19]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 58360291HCID 58360291, compound2×

Product 1

HCID 44540663HCID 44540663, compound

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

Methyl 5-(((2-(benzyloxy)ethyl)(4-fluorophenethyl)amino)methyl)-2,2-dimethyl-4H-[1,3]dioxino[4,5-c]pyridine-8-carboxylate (compound 26a) was reacted with formic acid according to the procedure described in example 21 step 21b. MS-ESI m/z 469 [MH]+.

Sources & evidence

ORD record
ord-f9be15a50a2545b9953e6db93e28ed46
Source dataset
uspto-grants-2014_06
Patent number
US08742123B2

Reaction notes

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