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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 402604Generated: October 29, 2026

Hydrochloric Acid → HCID 178469740, compound

https://huagongshe.com/reaction/402604

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant1H-Pyrrolo[2,3-b]pyridine-3-carbaldehydeHCID 5372812—
ReactantHCID 53331283HCID 53331283—
SolventEthanolHCID 702—
ProductHCID 178469740HCID 17846974056%

Reaction Steps

A solution of ethyl 2-(benzylamino)-4-oxo-4,5-dihydrofuran-3-carboxylate (0.026 g, 0.10 mmol) which similarly prepared according to the procedure described in the Example 2, First step and 7-azaindole-3-carboxaldehyde (0.015 g, 0.10 mmol) in 2M hydrochloric acid in ethanol (1.0 mL) was refluxed for 4 h. Cooled to ambient temperature, the precipitate was collected by filtration, washed with ethanol and diisopropyl ether then dried to afford the titled compound (0.024 g, y. 56%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08742113B2
Source datasetuspto-grants-2014_06
ORD IDord-eb846732b2b648309553005b6f3085b7
Source noteuspto-grants-2014_06