Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Dimethylformamide → 8-Chloro-4,4-dimethylthiochroman-6-carbaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Dimethylformamide | HCID 6228 | — |
| 반응물 | 6-Bromo-8-chloro-4,4-dimethylthiochroman | HCID 66764938 | — |
| 반응물 | Butyllithium | HCID 178418339 | — |
| 생성물 | 8-Chloro-4,4-dimethylthiochroman-6-carbaldehyde | HCID 86676817 | — |
반응 단계
Using essentially the same procedure as Example 5-20, Step 3, 6-bromo-8-chloro-4,4-dimethyl-3,4-dihydro-2H-thiochromene (954 mg, 3.27 mmol), n-BuLi (1.57 mL, 3.93 mmol) and DMF (1.01 mL, 13.1 mmol) afforded the desired product as a pale-yellow oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08742110B2 |
| 출처 데이터셋 | uspto-grants-2014_06 |
| ORD ID | ord-3489dc472502407298b694e9f83c8ba7 |
| 출처 메모 | uspto-grants-2014_06 |