反应详情

The title compound was prepared methyl 4-(2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)benzoate hydrochloride salt (80 mg, 0.245 mmol; Example 1, Step 2) and 1-bromo-5-(bromomethyl)-2,4-dichlorobenzene (86 mg, 0.269 mmol) following essentially the same procedure described in Step 1 of Example 7-9. The title compound was obtained as an off-white solid (129 mg) and was used without further purification.