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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 402834Generated: October 30, 2026

2-Bromo-4-(bromomethyl)-1-(trifluoromethyl)benzene → HCID 86685279, compound

https://huagongshe.com/reaction/402834

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-4-(bromomethyl)-1-(trifluoromethyl)benzeneHCID 18000985—
ReactantMethyl 4-(2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)benzoate hydrochloride saltHCID 66764605—
ProductHCID 86685279HCID 86685279—

Reaction Steps

The title compound was prepared from methyl 4-(2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)benzoate hydrochloride salt (50 mg, 0.153 mmol; Example 1, Step 2) and 2-bromo-4-(bromomethyl)-1-(trifluoromethyl)benzene (53.5 mg, 0.168 mmol) following essentially the same procedure described in Step 1 of Example 7-9. The title compound was obtained as a yellow oil (91 mg) that was used without any further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08742110B2
Source datasetuspto-grants-2014_06
ORD IDord-efa7320416e640fea1c8283aa576ba42
Source noteuspto-grants-2014_06