HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromo-4-(bromomethyl)-1-(trifluoromethyl)benzene → HCID 86685279, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromo-4-(bromomethyl)-1-(trifluoromethyl)benzene | HCID 18000985 | — |
| Reactant | Methyl 4-(2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)benzoate hydrochloride salt | HCID 66764605 | — |
| Product | HCID 86685279 | HCID 86685279 | — |
Reaction Steps
The title compound was prepared from methyl 4-(2-oxo-1-oxa-3,8-diazaspiro[4.5]dec-3-yl)benzoate hydrochloride salt (50 mg, 0.153 mmol; Example 1, Step 2) and 2-bromo-4-(bromomethyl)-1-(trifluoromethyl)benzene (53.5 mg, 0.168 mmol) following essentially the same procedure described in Step 1 of Example 7-9. The title compound was obtained as a yellow oil (91 mg) that was used without any further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08742110B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-efa7320416e640fea1c8283aa576ba42 |
| Source note | uspto-grants-2014_06 |