Ethylamine → N-ethyl-N,N-bis[2-(tert-butoxycarbonylamino)-3-cyclohexylpropyl]amine

HRID 402982Notes

Reaction equation

HRID 402982 reaction equation
[C:1]([O:5][C:6]([NH:8][C@@H:9]([CH2:12][CH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)[CH:10]=O)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH2:19]([NH2:21])[CH3:20]>>[CH2:19]([N:21]([CH2:10][CH:9]([NH:8][C:6]([O:5][C:1]([CH3:2])([CH3:4])[CH3:3])=[O:7])[CH2:12][CH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)[CH2:10][CH:9]([NH:8][C:6]([O:5][C:1]([CH3:4])([CH3:3])[CH3:2])=[O:7])[CH2:12][CH:13]1[CH2:18][CH2:17][CH2:16][CH2:15][CH2:14]1)[CH3:20]

Participants

3

Reactant 2

HCID 6341EthylamineHCID 10848617(S)-Tert-butyl 1-cyclohexyl-3-oxopropan-2-ylcarbamate

Product 1

HCID 60204727N-ethyl-N,N-bis[2-(tert-butoxycarbonylamino)-3-cyclohexylpropyl]amine

Procedure

The product from Example 15A and ethylamine were processed as described in Example 7B to provide the title compound.

Sources & evidence

ORD record
ord-c500798979484aa28e027663f1a69382
Source dataset
uspto-grants-2014_06
Patent number
US08741938B2

Reaction notes

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