HCID 42645993, compound → N,N-bis[(2R)-2-(tert-butoxycarbonylamino)-3-phenylpropyl]amine

HRID 403003Notes

Reaction equation

HRID 403003 reaction equation
[NH2:1][CH2:2][C@H:3]([NH:11][C:12](=[O:18])[O:13][C:14]([CH3:17])([CH3:16])[CH3:15])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[C:19]([O:23][C:24]([N:26]1[CH2:28][C@H:27]1[CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)=[O:25])([CH3:22])([CH3:21])[CH3:20]>>[C:14]([O:13][C:12]([NH:11][C@H:3]([CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)[CH2:2][NH:1][CH2:28][C@H:27]([NH:26][C:24]([O:23][C:19]([CH3:20])([CH3:22])[CH3:21])=[O:25])[CH2:29][C:30]1[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=1)=[O:18])([CH3:15])([CH3:17])[CH3:16]

Participants

3

Reactant 2

HCID 42645993HCID 42645993, compoundHCID 60204744(2R)-N-tert-butoxycarbonyl-2-phenylmethylaziridine

Product 1

HCID 60204745N,N-bis[(2R)-2-(tert-butoxycarbonylamino)-3-phenylpropyl]amine

Procedure

The product from Example 70C and the product from Example 70A were processed as described in Example 1D to provide the title compound.

Sources & evidence

ORD record
ord-190144e5a7734fafaeb7056df09d39ef
Source dataset
uspto-grants-2014_06
Patent number
US08741938B2

Reaction notes

Loading…