Trifluoroacetic acid → HCID 86659579, compound

Participants

Reaction Steps

An amount of 120 mg (0.096 mmol) of the compound from example 27A was introduced in 1 ml of dichloromethane, admixed with 0.074 ml (0962 mmol) of trifluoroacetic acid and stirred at RT overnight. The reaction mixture was then concentrated and the residue was purified by means of preparative HPLC (eluent gradient: acetonitrile/water 10:90→95:5 with addition of 0.1% TFA). This gave 20 mg (18% of theory) of the target compound.

Provenance & Evidence