Trifluoroacetic acid → HCID 88545534, compound

Participants

Reaction Steps

An amount of 85 mg (0.077 mmol) of the compound from example 33A was introduced in 0.5 ml of dichloromethane, admixed with 0.059 ml (0.771 mmol) of trifluoroacetic acid and stirred at RT overnight. The reaction mixture was then concentrated and the residue was purified by means of preparative HPLC (eluent gradient: acetonitrile/water 10:90→95:5 with addition of 0.1% TFA). This gave 47 mg (51% of theory) of the target compound.

Provenance & Evidence