HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(3-Aminopropyl)morpholine → 3-(4-chlorobenzyl)-N-(3-morpholinopropyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(3-Aminopropyl)morpholine | HCID 61055 | — |
| Reactant | 3-(4-Chlorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid | HCID 45031015 | — |
| Product | 3-(4-chlorobenzyl)-N-(3-morpholinopropyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide | HCID 25196745 | — |
Reaction Steps
30 mg (25%) of the target compound was obtained in the same manner of Example 1, using 3-(4-chloro-benzyl)-2,4-dioxoquinazoline-7-carboxylic acid (90 mg, 0.272 mol) obtained in Example 1 and 3-morpholine-4-yl-propylamine (87 mL, 0.598 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748422B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-1b8c379e916749f4a382a3c575fb2fa7 |
| Source note | uspto-grants-2014_06 |