HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Ethylpiperidin-1-yl)propan-1-amine → 3-(4-chlorobenzyl)-N-(3-(2-ethylpiperidin-1-yl)propyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Ethylpiperidin-1-yl)propan-1-amine | HCID 4117479 | — |
| Reactant | 3-(4-Chlorobenzyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxylic acid | HCID 45031015 | — |
| Product | 3-(4-chlorobenzyl)-N-(3-(2-ethylpiperidin-1-yl)propyl)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-7-carboxamide | HCID 16066792 | — |
Reaction Steps
55 mg (42%) of the target compound was obtained in the same manner of Example 1, using 3-(4-chloro-benzyl)-2,4-dioxoquinazoline-7-carboxylic acid (90 mg, 0.272 mmol) obtained in Example 1 and 3-(2-ethyl-piperidine-1-yl)-propylamine (101 mL, 0.598 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748422B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-c408deb9867d46a59cde7c3d985b9522 |
| Source note | uspto-grants-2014_06 |