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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 40335Generated: October 26, 2026

1-Ethyl-1H-pyrazole-4-boronic acid, pinacol ester → 4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole

https://huagongshe.com/reaction/40335

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Ethyl-1H-pyrazole-4-boronic acid, pinacol esterHCID 11379045—
Reactant4-bromo-1-(2,2,2-trifluoroethyl)-1H-pyrazoleHCID 61030283—
Product4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazoleHCID 68923586—

Reaction Steps

The title compound was prepared in the same manner as 1-ethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole starting with 4-bromo-1-(2,2,2-trifluoroethyl)-1H-pyrazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08524900B2
Source datasetuspto-grants-2013_09
ORD IDord-a07091baa6d246059b7fb18ca9a2d42d
Source noteuspto-grants-2013_09