3-Amino-4-bromo-6-chloropyridazine → 6-Chloro-4-[2-(2,2,2-trifluoro-ethoxy)-pyridin-3-yl]-pyridazin-3-ylamine

Participants

Reaction Steps

The title compound was prepared in analogy to example 1, intermediate b, from 4-bromo-6-chloro-pyridazin-3-ylamine (CAS RN 446273-59-2) and 2-(2,2,2-trifluoroethoxy)pyridine-3-boronic acid (CAS RN 1218790-79-4) after a reaction time of 18 hours. Brown solid (43%). MS (ESI+): m/z=305.041 ([M+H]+).

Provenance & Evidence