HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 16220808, compound → HCID 82374856, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 16220808 | HCID 16220808 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 82374856 | HCID 82374856 | 786.4% |
Reaction Steps
4-Chloro-5-nitro-6-o-tolyl-pyrimidine (580 mg, 0.23 mmol) and 10% palladium on carbon (125 mg, 0.116 mmol) in ethanol were stirred under 1 atmosphere of hydrogen pressure for 16 hours. Filtration followed by removal of volatiles gave the desired compound as a yellow solid (335 mg, 78%) which was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08748434B2 |
| Source dataset | uspto-grants-2014_06 |
| ORD ID | ord-8aea7f5bd80840aeac9d5bd792bad0f7 |
| Source note | uspto-grants-2014_06 |