HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Trifluoroacetic acid → [4-(5-Cyclopentyloxy-7-propoxy-oxazolo[5,4-d]pyrim idin-2-yl)-2,6-dimethyl-phenoxy]-acetic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Trifluoroacetic acid | HCID 6422 | — |
| Edukt | [4-(5-Cyclopentyloxy-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethyl-phenoxy]-acetic acid tert-butyl ester | HCID 86679898 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | [4-(5-Cyclopentyloxy-7-propoxy-oxazolo[5,4-d]pyrim idin-2-yl)-2,6-dimethyl-phenoxy]-acetic acid | HCID 53311353 | 108,2% |
Reaktionsschritte
25 mg of [4-(5-cyclopentyloxy-7-propoxy-oxazolo[5,4-d]pyrimidin-2-yl)-2,6-dimethyl-phenoxy]-acetic acid tert-butyl ester were dissolved in 2 ml of dichloromethane and treated with 1 nil of trifluoroacetic acid. After 16 h the mixture was concentrated and freeze-dried. 24 mg of the title compound were obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08748436B2 |
| Quelldatensatz | uspto-grants-2014_06 |
| ORD ID | ord-f0a4d15b90d148558f23dcb0955982f0 |
| Quellennotiz | uspto-grants-2014_06 |