Benzenesulfonyl chloride → HCID 66689130, compound

HRID 403545Notes

Reaction equation

HRID 403545 reaction equation
[CH3:1][NH:2][CH:3]([C:5]1[N:14]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:13](=[O:21])[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]=1)[CH3:4].[C:22]1([S:28](Cl)(=[O:30])=[O:29])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1>>[CH3:1][N:2]([CH:3]([C:5]1[N:14]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[C:13](=[O:21])[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[N:6]=1)[CH3:4])[S:28]([C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)(=[O:30])=[O:29]

Participants

3

Reactant 2

HCID 7369Benzenesulfonyl chlorideHCID 42711256HCID 42711256, compound

Product 1

HCID 66689130HCID 66689130, compound

Procedure

In a similar manner as described above in Example 7, 2-(1-methylaminoethyl)-3-phenyl-3H-quinazolin-4-one, prepared as described above in Paragraph A, was condensed with benzenesulfonyl chloride to yield N-methyl-N-[1-(4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl]benzenesulfonamide; MS (ESI) 420 (MH+).

Workup

  1. customprepared

Sources & evidence

ORD record
ord-c3fe5c9bed5c495e84b35d06ebb38419
Source dataset
uspto-grants-2014_06
Patent number
US08748440B2

Reaction notes

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