反应详情

3-tert-Butyl-5-iodo-4-methoxyaniline (915 mg, 3.0 mmol) and chloroacetyl isocyanate (0.256 mL, 3.00 mmol) were reacted in the same manner as Example 14 Part A to give crude product which was purified on an Isco 40 g silica cartridge eluting with methanol/dichloromethane (0% to 5%) to give the title compound.

1. customto give crude product which
2. customwas purified on an Isco 40 g silica cartridge
3. washeluting with methanol/dichloromethane (0% to 5%)